|
Bacteriophage P2 is a temperate phage that infects ''E. coli''. It is a tailed virus with a contractile sheath and is thus classified in the family ''Myoviridae'' and the order ''Caudovirales''. This class of viruses includes many P2-like phages as well as the satellite phage P4. ==Discovery== Bacteriophage P2 was first isolated by G. Bertani from the Lisbonne and Carrère strain of ''E. coli'' in 1951.〔Bertani, G., ''STUDIES ON LYSOGENESIS I.: The Mode of Phage Liberation by Lysogenic Escherichia coli1.'' Journal of bacteriology, 1951. 62(3): p. 293.〕 Since that time, a large number of P2-like prophages (e.g. 186, HP1, HK239, and WΦ) have been isolated that shared characters such as host range, serological relatedness and inability to recombine with phage λ, and they seemed to be quite common in ''E. coli'' populations as about 30% of the strains in the ''E. coli'' reference collection (ECOR) contain P2-like prophages .〔Nilsson, A.S., J.L. Karlsson, and E. Haggård-Ljungquist, ''Site-specific recombination links the evolution of P2-like coliphages and pathogenic enterobacteria.'' Molecular biology and evolution, 2004. 21(1): p. 1-13.〕 Of these P2-like prophages is P2 best characterized. The P2 phage was found to be able to multiply in many strains of ''E. coli'', as well as in strains of many other species including ''Serratia'', ''Klebsiella pneumoniae'', and ''Yersinia'' sp,〔Haggård-Ljungquist, E., C. Halling, and R. Calendar, ''DNA sequences of the tail fiber genes of bacteriophage P2: evidence for horizontal transfer of tail fiber genes among unrelated bacteriophages.'' Journal of bacteriology, 1992. 174(5): p. 1462-1477.〕 which suggested that it played an important role in horizontal gene transfer in bacterial evolution. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Enterobacteria phage P2」の詳細全文を読む スポンサード リンク
|